In Rome, a perfume atomizer containing a secret formula injects a burst of adventure into the
drab life of tourist Darlene Sims.

Dr. Kharmusi, a criminal scientist, has developed a "thermal prism," which generates intense
heat beams. UNCLE recruits Luther Sebastian, wanted for various crimes in 22 countries,
because he designed the kind of safe where Kharmusi keeps the prism. Napoleon Solo
infiltrates Kharmusi's base of operations as an amoral businessman while Illya Kuryakin
and Sebastian work to steal the device. However, Annie, whose boyfriend was framed for
murder by Sebastian, complicates matters.